Causes Of Hemoglobinuria: Symptoms, Diagnosis, And Treatment


Hemoglobinuria is a condition in which hemoglobin from the blood is excreted with urine in abnormally high amounts. Various factors like burns, renal cancer, malaria, sick cell anemia, and acute lead poisoning can contribute to this condition’s development. We’ll tell you all that you should know about hemoglobinuria, its causes, associated symptoms, diagnosis, and methods used for treatment. There are several health conditions that you may get as a result of a poor lifestyle, unhealthy food, and other physical factors. But do you what Hemoglobinuria is? And what are the causes leading to this disease in your body? Let us discuss it in detail.

What do you mean by Hemoglobinuria?
Hemoglobinuria is often associated with hemolytic anemia, a condition in which RBCs are destroyed. This issue leads to an increase in free plasma hemoglobin, after which excess hemoglobin is filtered by the kidneys and excreted with urine. This excess hemoglobin gives urine an unusual purple color. The diagnosis of hemoglobinuria is often based on collected blood samples, urine samples, and a study of the patient’s medical history. Various causes such as acute glomerulonephritis, renal cancer, malaria, sickle cell anemia, and tuberculosis of the urinary tract can cause hemoglobinuria as a symptom.
We’ll tell you all that you should know about the condition, causes of hemoglobinuria: symptoms, diagnosis and treatment, and everything else you need to about this condition.

What Causes Hemoglobinuria?
In hemoglobinuria, the quantity or concentration of free hemoglobin in the blood plasma significantly increases. This excess hemoglobin is then filtered by the kidneys and excreted with urine, giving it a somewhat purple color. Hemoglobinuria is often caused as a secondary health complication induced by another underlying cause of disease. The following is a list of some causes of hemoglobinuria:
⦁ Burns
⦁ Acute glomerulonephritis
⦁ Malaria
⦁ Renal Cancer
⦁ Microangiopathy
⦁ Paroxysmal nocturnal hemoglobinuria
⦁ Autoimmune hemolytic anemia
⦁ Transfusion reactions
⦁ Sickle cell anemia
⦁ Pyelonephritis
⦁ March hemoglobinuria
⦁ Tuberculosis of the urinary tract
⦁ Acute lead poisoning
⦁ Athletic nephritis
Hemoglobinuria is usually a result of other health conditions, such as the ones mentioned above. Usually, the condition can be easily treated by curing the underlying disease or health condition that induces hemoglobinuria and its symptoms.

Symptoms of Hemoglobinuria
Hemoglobinuria doesn’t have any specific symptoms. The only symptom that the condition shows is hemoglobin present in the urine, which causes it to appear tea-colored, or reddish-brown. Sometimes, hemoglobinuria can also lead to a condition known as acute tubular necrosis.
While hemoglobinuria doesn’t show any symptoms other than a change in urine color, certain other symptoms caused by the underlying disease may be observed. However, there still are some symptoms that are commonly observed in the presence of this condition. The following are some such symptoms:
⦁ Increase in Quantity of Urine: When affected by hemoglobinuria, individuals can often notice slight increments in the quantity of urine they micturate.
⦁ Increase in Frequency of Passage of Urine: Urine is often passed more frequently by people affected by hemoglobinuria than their usual or normal routines.
⦁ Malaise: If you’re suffering from hemoglobinuria, the chances are that you will also experience malaise. You might experience some discomfort, uneasiness, or illness for reasons that may not be easy to figure out.
⦁ Chills: Chills can also be commonly experienced during the presence of hemoglobinuria. While chills can often occur for no considerable reason, they tend to become more frequent with the presence of hemoglobinuria.
⦁ Fever: Hemoglobinuria can also induce fever. While it’s not always the cause of fever, this symptom can be experienced with the condition. Fever, along with other characteristic symptoms of hemoglobinuria, can be a sign of having been affected by the condition.
⦁ Pain in Loins: Hemoglobinuria can also cause some pain in the loins. While injuries and other conditions can also cause this, a possible cause of this symptom is hemoglobinuria. The condition can produce biological issues that may result in pain in the loins.
⦁ Diarrhea: Diarrhea can have a lot of causes, and one of them is hemoglobinuria. Hemoglobinuria can produce changes that can cause diarrhea in affected individuals.
⦁ Slight Nausea: If you’re suffering from hemoglobinuria, you may also experience some minor nausea and vomiting.

Diagnosis
Diagnosis of hemoglobinuria is usually carried out based on the patients’ medical history, the study of their collected blood samples, and the study of urine samples. Hemoglobin is normally absent in the urine, which is why urine samples are checked for hemoglobin for the diagnosis of hemoglobinuria.

Treatment of This Condition
All that the treatment of hemoglobinuria involves is the diagnosis of the underlying problems; however, it still is performed in a certain set and order of procedures.
This is how the treatment of hemoglobinuria is performed:
⦁ Identification of Hemoglobinuria: The symptoms caused by hemoglobinuria can also appear due to other health issues, which is why the condition and the symptoms produced by it are studied to identify the actual condition. Once hemoglobinuria is confirmed, the patient is checked for the presence of any underlying health problems.
⦁ Study of Associated Symptoms: Once hemoglobinuria is confirmed with its diagnosis, the patient’s additional symptoms are studied for the identification of the condition that had been causing it.
⦁ Diagnosis of Underlying Issue: The underlying issue is checked and diagnosed for confirmation before carrying out the treatment. The condition is diagnosed until confirmed, after which it is treated using the appropriate treatment methods.
⦁ Elimination of the Underlying Health Problem: Once identified, the underlying disease or health condition is treated and cured, which, in turn, also cures hemoglobinuria. Hemoglobinuria is a symptom in itself, and it can only be treated by applying the appropriate treatment for the underlying cause.
⦁ Countering any Effects Produced: Once the underlying health issue is cured, any biological effects produced by it or any resultant symptoms are treated and cured by applying the appropriate methods.

Hemoglobinuria is caused by underlying health issues, which is why it has no particular treatment procedure. The disease or health problem which causes Hemoglobinuria is identified and treated; and, once cured, also eliminates Hemoglobinuria and its symptoms.

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